Welcome to our little (but growing) Parker world.
Lots of folks run that same rig with 225 ponies and seem to do OK. Remember, that with a 16 degree deadrise, you aren't going to be screaming through the chop. The F250 on that hull should be fairly economical also, and in the days of $3.50-$4.00 a gal gas on the water, sipping that liquid gold becomes important.
I have twin F115s on a 2510 with 14 deg of deadrise. They will cruise the boat faster than the Ches Bay chop will allow most of the time. It is only on those occassional days where the waves are less than 1' where I wish I could cruise at 30 mph. But, on a normal day I get about 23-25 mph @ 4,200 rpm, and between 8.5 and 10.0 gph depending on motor trim and tab settings.
One/more folks with your desired setup should be able to chime in here with some accurate, first-hand figures.