FWIW anytime, as in ANY ... when I am moving at headway speeds, I always trim the motor up & out.
Not only does this position the OB for the best thrust when in reverse, but it significantly improves your headway speed MPG/fuel efficiency, as in I'll realize a good 20% or MORE improvement, when the OB lower unit is up higher than the bottom of the hull or thereabouts. As verified by a fuel computer.
Just trim her up so you still get good water flow and you'll be all set!